What is umbilical cord mesenchymal stem cell banking or MSC expansion?
MSC expansion is the process of growing or multiplying an initial number of MSCs. In stem cell therapies, a specific stem cell count (stem cell dose) is required to provide therapeutic effectiveness.
Readily Expanded MSCs: For Your Family’s Medical Preparedness
MSCs from cord tissue are some of the youngest cells that can be collected safely and painlessly at birth and when expanded, can have the potential to renew and regenerate many other cell types in your body. When you bank these expanded cells, they are suspended in time and will never age. You can withdraw them anytime and use them at their best state.
TREATMENT-READY Stem Cells
By having your baby’s MSCs expanded now, you and your family members can immediately access medical care without possible delays.
WORLD-CLASS Facilities
Besides being ISO-certifed and DOH-registered, both processing and storage facilities adhere to the
best practices globally and adopt strict protocols from collection, processing,
expansion and cryopreservation of your baby’s MSCs period after MSCs
FREE 5-year Storage
After your baby’s MSCs have been expanded by MMC-CRM,
Cordlife will give you free storage for your baby’s expanded MSCs for the first five years in case there is no immediate necessity.
MULTIPLE Storage Method
Your baby’s MSCs will be preserved in multiple cryovials so that you and your family have the opportunity to use the cells for more than one medical treatment.
STRINGENT Quality Control
Your baby’s MSCs will undergo meticulous quality testing to confirm that your baby’s MSCs can be used for future medical treatment.
Potential Applications with MSCs
Currently, there are almost 1,000* clinical trials ongoing worldwide aimed at uncovering the potential of MSCs and these cells can also be found in your baby’s umbilical cord tissue. Here are some of the clinical indications investigated now.
Tissue repair
- Stroke
- Cardiovascular diseases
- Neurodegenerative diseases (Alzheimer’s Disease and Parkinson’s Disease)
- Autism, Cerebral Palsy, and Global Developmental Delay
- Spinal cord injury
- Orthopedic indications such as osteoarthritis and cartilage repair
- Liver regeneration from liver failure
- Pneumonia with COVID-19
Immune modulation or Reconstruction
- HIV
- Diabetes (type 1 and 2)
- Graft-versus-host disease
- Crohn’s disease
HSCs engraftment support
- Shortened engraftment time and reduced immune system complications
* NIH U.S. National Library of Medicine. www.clinical trials.gov. Search term used “mesenchymal stem cells”. Last accessed 2 March 2020.
The Philippines’ First And Only Stem Cell Bank Offering Mesenchymal Stem Cell Expansion
in partnership with Makati Medical Center’s Center for Regenerative Medicine (MMC-CRM).
While most cord blood banks can only offer storage of stem cells, we at Cordlife are always one step ahead. Through the expertise of our partner, Makati Medical Center’s Center for Regenerative Medicine (MMC-CRM), we can now expand your baby’s MSCs.
MMC-CRM provides viable alternative or adjunct cutting-edge stem cell treatment for chronic, autoimmune, and degenerative diseases such as cancer, multiple sclerosis, ischemic cardiomyopathy, psoriasis and osteoarthritis.
The facility is accredited by the Department of Health (DOH) as a facility that may engage in human stem cell or cellular therapy in accordance with Administrative Order No. 2013-012. The center adheres to global standards in cellular therapeutics practice, training and research, and staffed by experienced scientists dedicated to excellence in healthcare.
6 Easy Steps To Preserve Your Baby’s Expanded MSCs
Step 1:
Receive your collection
kit upon enrolment with
Cordlife via face-to-face or
virtual consultation.
Step 2:
Inform your OB-GYN that you
have decided to do umbilical
cord expanded MSC banking.
Step 3:
Bring your collection
kit to the hospital on
the day of delivery.
Step 4:
After your OB-GYN has
collected your baby’s
umbilical cord tissue, call us
for the pick-up of the sample.
Step 5:
The MMC-CRM will
process the expansion of
the MSCs from your baby’s
umbilical cord tissue.
Step 6:
Once the MSCs have been
expanded, it will be stored in
Cordlife’s facility and will be
available for your family’s use.
What Experts Say About Preserving Expanded MSCs
MSCs from Wharton’s jelly of the umbilical cord have innate capability to migrate towards damaged tissues, affect growth of blood vessels, suppress immunity, induce an anti-inflammatory reaction, and even prevent cell death. MSCs have already been safely transplanted prenatally via ultrasound-guided injection into umbilical cord. This makes fetal MSCs a novel area of interest in the field of in-utero stem cell transplantation for treatment of congenital disease.
Rebecca Singson, MD, FPOGS, FPSGE
Robotic Surgeon/Laparoscopic Surgeon
Obstetrician-Gynecologist, St. Luke’s BGC, Makati Medical Center, Asian Hospital
Rebecca Singson, MD, FPOGS, FPSGE
Robotic Surgeon/Laparoscopic Surgeon
Obstetrician-Gynecologist, St. Luke’s BGC, Makati Medical Center, Asian Hospital
Mesenchymal stem cells have been the subject of investigation for the past few decades in animal models and pre-clinical research. The time has come to translate this wealth of information into clinical trials in our country. This is necessary since any potential medical treatment needs to be thoroughly evaluated to determine the right dose, right timing, and right indication. Aside from known properties and mechanisms of action, there could be added information that may be elucidated depending on the source of MSC or the specific disease process. For example, we now know that the administered MSCs do not live indefinitely but exert their immunomodulatory and regenerative effects thru bioactive molecules termed extracellular vesicles (EV). Data from carefully planned human studies may then be utilized in basic research to continue the endless cycle of scientific learning.
Arvin Faundo, MD, FPSP
Medical Director, Cordlife Philippines and Cordlife Indonesia
Arvin Faundo, MD, FPSP
Medical Director, Cordlife Philippines and Cordlife Indonesia
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